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VRTX · Vertex Pharmaceuticals

USDPartial · stale

Sources: StockAnalysis

Saved price$542.62
Analyst 12M target
$582.87
Difference from current price
+7.4%
12M target range
$350.00 – $725.00
Estimate agreement
39%

Price history & SEC filings

Up day Down day SEC filing
2026-09-16
Open
$513.80
High
$517.95
Low
$511.90
Close
$514.86
Change
+0.2%
Volume
70.5K

Price and SEC filing data

  • 2026-03-16: Open $475.14, High $476.17, Low $461.13, Close $466.10, Volume 1.5M.
  • 2026-03-17: Open $468.40, High $468.45, Low $461.50, Close $462.49, Volume 1.5M.
  • 2026-03-18: Open $462.80, High $463.96, Low $451.10, Close $451.59, Volume 1.4M.
  • 2026-03-19: Open $454.50, High $459.46, Low $449.75, Close $458.05, Volume 1.3M.
  • 2026-03-20: Open $454.62, High $461.05, Low $452.89, Close $454.00, Volume 2.2M.
  • 2026-03-23: Open $458.42, High $463.78, Low $450.97, Close $451.24, Volume 1.2M.
  • 2026-03-24: Open $447.02, High $452.08, Low $441.20, Close $448.62, Volume 1.2M.
  • 2026-03-25: Open $449.14, High $459.37, Low $449.14, Close $454.97, Volume 1.2M.
  • 2026-03-26: Open $450.72, High $457.54, Low $449.29, Close $453.74, Volume 1.2M.
  • 2026-03-27: Open $450.95, High $452.00, Low $431.01, Close $433.07, Volume 1.9M.
  • 2026-03-30: Open $438.73, High $443.65, Low $432.14, Close $443.16, Volume 2M.
  • 2026-03-31: Open $443.43, High $448.35, Low $442.09, Close $446.54, Volume 1.6M.
  • 2026-04-01: Open $449.17, High $453.98, Low $446.71, Close $447.26, Volume 1.2M.
  • 2026-04-02: Open $447.55, High $449.62, Low $436.56, Close $438.71, Volume 1.2M.
  • 2026-04-06: Open $437.79, High $440.90, Low $433.45, Close $434.30, Volume 948.9K.
  • 2026-04-07: Open $435.50, High $435.50, Low $425.26, Close $431.86, Volume 1M.
  • 2026-04-08: Open $436.25, High $443.99, Low $432.33, Close $443.92, Volume 1.3M.
  • 2026-04-09: Open $439.77, High $447.00, Low $436.35, Close $446.78, Volume 1M.
  • 2026-04-10: Open $446.08, High $446.75, Low $434.25, Close $436.27, Volume 985.8K.
  • 2026-04-13: Open $434.17, High $445.11, Low $433.68, Close $440.05, Volume 1M.
  • 2026-04-14: Open $435.28, High $444.79, Low $435.28, Close $444.28, Volume 1.4M.
  • 2026-04-15: Open $444.15, High $447.82, Low $437.19, Close $441.70, Volume 1.5M.
  • 2026-04-16: Open $442.35, High $445.93, Low $431.15, Close $435.65, Volume 1.4M.
  • 2026-04-17: Open $441.55, High $443.90, Low $437.58, Close $441.20, Volume 1M.
  • 2026-04-20: Open $444.01, High $444.01, Low $437.67, Close $439.18, Volume 789.2K.
  • 2026-04-21: Open $437.12, High $440.32, Low $429.65, Close $436.59, Volume 986.9K.
  • 2026-04-22: Open $437.38, High $441.00, Low $435.45, Close $437.67, Volume 734.2K.
  • 2026-04-23: Open $440.71, High $442.04, Low $433.81, Close $435.10, Volume 777.5K.
  • 2026-04-24: Open $431.89, High $433.68, Low $427.38, Close $430.29, Volume 1.1M.
  • 2026-04-27: Open $427.01, High $434.07, Low $425.87, Close $426.01, Volume 967K.
  • 2026-04-28: Open $431.25, High $431.77, Low $426.68, Close $430.14, Volume 808.5K.
  • 2026-04-29: Open $424.44, High $426.72, Low $419.71, Close $423.24, Volume 1.1M.
  • 2026-04-30: Open $423.66, High $430.95, Low $423.66, Close $427.38, Volume 1.1M.
  • 2026-05-01: Open $425.02, High $427.38, Low $421.54, Close $423.92, Volume 796.9K.
  • 2026-05-04: Open $423.75, High $430.13, Low $422.11, Close $429.85, Volume 1.4M.
  • 2026-05-05: Open $431.99, High $433.94, Low $412.27, Close $424.36, Volume 1.9M.
  • 2026-05-06: Open $422.67, High $431.06, Low $422.67, Close $427.65, Volume 1.2M.
  • 2026-05-07: Open $425.13, High $429.61, Low $423.59, Close $425.00, Volume 1.1M.
  • 2026-05-08: Open $422.37, High $431.94, Low $421.11, Close $429.82, Volume 953.3K.
  • 2026-05-11: Open $429.50, High $442.16, Low $428.50, Close $435.17, Volume 1.3M.
  • 2026-05-12: Open $439.92, High $454.23, Low $436.48, Close $448.29, Volume 1.4M.
  • 2026-05-13: Open $446.47, High $455.32, Low $444.26, Close $453.06, Volume 1.2M.
  • 2026-05-14: Open $453.64, High $456.68, Low $447.36, Close $450.41, Volume 1.1M.
  • 2026-05-15: Open $453.45, High $453.45, Low $435.86, Close $436.95, Volume 1.3M.
  • 2026-05-18: Open $435.42, High $440.04, Low $430.25, Close $436.58, Volume 1.5M.
  • 2026-05-19: Open $436.79, High $444.32, Low $433.15, Close $434.31, Volume 1.2M.
  • 2026-05-20: Open $434.31, High $439.98, Low $427.64, Close $430.44, Volume 1.8M.
  • 2026-05-21: Open $429.36, High $434.76, Low $426.01, Close $433.54, Volume 1.4M.
  • 2026-05-22: Open $437.07, High $438.84, Low $432.96, Close $434.52, Volume 1.7M.
  • 2026-05-26: Open $437.99, High $441.99, Low $433.79, Close $435.93, Volume 865.8K.
  • 2026-05-27: Open $438.52, High $445.35, Low $435.39, Close $437.22, Volume 1.2M.
  • 2026-05-28: Open $434.08, High $449.29, Low $434.08, Close $447.97, Volume 1.4M.
  • 2026-05-29: Open $448.01, High $450.00, Low $442.25, Close $447.54, Volume 1.9M.
  • 2026-06-01: Open $439.91, High $443.54, Low $433.26, Close $438.40, Volume 1.1M.
  • 2026-06-02: Open $432.40, High $434.00, Low $424.90, Close $425.09, Volume 1.1M.
  • 2026-06-03: Open $420.63, High $429.01, Low $420.01, Close $428.34, Volume 1.6M.
  • 2026-06-04: Open $434.95, High $448.19, Low $433.50, Close $441.74, Volume 1.4M.
  • 2026-06-05: Open $445.61, High $453.16, Low $443.86, Close $446.83, Volume 1.5M.
  • 2026-06-08: Open $443.17, High $448.69, Low $441.72, Close $442.96, Volume 1.1M.
  • 2026-06-09: Open $447.02, High $449.50, Low $440.90, Close $445.77, Volume 871.2K.
  • 2026-06-10: Open $447.27, High $447.50, Low $433.80, Close $435.71, Volume 1.1M.
  • 2026-06-11: Open $437.51, High $445.78, Low $435.21, Close $445.04, Volume 1.2M.
  • 2026-06-12: Open $440.02, High $447.70, Low $440.02, Close $444.93, Volume 924.2K.
  • 2026-06-15: Open $446.69, High $453.68, Low $439.50, Close $450.46, Volume 1.5M.
  • 2026-06-16: Open $452.82, High $454.55, Low $444.22, Close $453.17, Volume 1.5M.
  • 2026-06-17: Open $449.67, High $464.31, Low $447.54, Close $458.99, Volume 1.5M.
  • 2026-06-18: Open $462.17, High $464.98, Low $450.39, Close $451.63, Volume 3M.
  • 2026-06-22: Open $455.65, High $468.18, Low $453.21, Close $466.79, Volume 2M.
  • 2026-06-23: Open $469.67, High $470.82, Low $463.76, Close $468.42, Volume 1.2M.
  • 2026-06-24: Open $471.38, High $480.86, Low $469.93, Close $475.20, Volume 1.6M.
  • 2026-06-25: Open $475.11, High $486.49, Low $473.50, Close $480.18, Volume 1.5M.
  • 2026-06-26: Open $482.50, High $503.89, Low $482.20, Close $491.34, Volume 8.7M.
  • 2026-06-29: Open $495.83, High $499.87, Low $487.62, Close $499.65, Volume 2.1M.
  • 2026-06-30: Open $500.49, High $500.99, Low $489.62, Close $496.73, Volume 1.7M.
  • 2026-07-01: Open $502.71, High $502.71, Low $494.80, Close $498.01, Volume 1.4M.
  • 2026-07-02: Open $503.76, High $529.14, Low $501.53, Close $528.04, Volume 1.9M.
  • 2026-07-06: Open $526.67, High $529.99, Low $512.34, Close $529.59, Volume 1.5M.
  • 2026-07-07: Open $530.00, High $533.67, Low $512.77, Close $522.25, Volume 2.3M.
  • 2026-07-08: Open $523.04, High $525.81, Low $498.14, Close $498.43, Volume 2.3M.
  • 2026-07-09: Open $495.58, High $500.77, Low $482.11, Close $496.50, Volume 2.1M.
  • 2026-07-10: Open $498.15, High $498.91, Low $484.33, Close $485.39, Volume 1.4M.
  • 2026-07-13: Open $486.18, High $486.18, Low $474.71, Close $480.25, Volume 1.2M.
  • 2026-07-14: Open $481.29, High $481.29, Low $473.18, Close $476.31, Volume 1.1M.
  • 2026-07-15: Open $472.15, High $480.96, Low $469.60, Close $477.08, Volume 1.2M.
  • 2026-07-16: Open $480.00, High $487.30, Low $476.25, Close $486.03, Volume 1.4M.
  • 2026-07-17: Open $483.51, High $496.69, Low $481.98, Close $485.65, Volume 1.6M.
  • 2026-07-20: Open $485.65, High $491.23, Low $478.48, Close $480.50, Volume 1.1M.
  • 2026-07-21: Open $478.56, High $484.99, Low $473.56, Close $482.00, Volume 1.1M.
  • 2026-07-22: Open $482.32, High $483.66, Low $471.58, Close $472.57, Volume 1.3M.
  • 2026-07-23: Open $467.09, High $477.68, Low $465.00, Close $473.09, Volume 1.3M.
  • 2026-07-24: Open $476.05, High $484.00, Low $472.58, Close $477.36, Volume 1.3M.
  • 2026-07-27: Open $479.27, High $487.21, Low $477.99, Close $479.00, Volume 1.6M.
  • 2026-07-28: Open $483.13, High $493.61, Low $482.86, Close $490.39, Volume 1.7M.
  • 2026-07-29: Open $492.67, High $492.99, Low $481.91, Close $483.33, Volume 1.5M.
  • 2026-07-30: Open $474.10, High $482.15, Low $470.54, Close $481.70, Volume 1.2M.
  • 2026-07-31: Open $480.67, High $480.67, Low $469.87, Close $477.10, Volume 957.7K.
  • 2026-08-03: Open $480.00, High $483.36, Low $468.14, Close $470.72, Volume 1.5M.
  • 2026-08-04: Open $471.29, High $488.04, Low $465.51, Close $478.71, Volume 2M.
  • 2026-08-05: Open $487.52, High $491.95, Low $479.02, Close $484.83, Volume 1.4M.
  • 2026-08-06: Open $490.91, High $492.40, Low $480.86, Close $484.03, Volume 1M.
  • 2026-08-07: Open $487.11, High $497.40, Low $482.10, Close $496.07, Volume 992.4K.
  • 2026-08-10: Open $539.50, High $546.17, Low $519.82, Close $523.91, Volume 2.7M.
  • 2026-08-11: Open $525.02, High $532.23, Low $522.01, Close $529.65, Volume 1.1M.
  • 2026-08-12: Open $527.00, High $531.22, Low $520.08, Close $525.73, Volume 1M.
  • 2026-08-13: Open $528.68, High $529.00, Low $515.74, Close $516.44, Volume 863.5K.
  • 2026-08-14: Open $511.41, High $513.64, Low $502.29, Close $505.75, Volume 1.1M.
  • 2026-08-17: Open $503.87, High $517.84, Low $502.53, Close $515.55, Volume 1.1M.
  • 2026-08-18: Open $520.00, High $533.78, Low $517.34, Close $528.19, Volume 1.5M.
  • 2026-08-19: Open $537.47, High $553.69, Low $532.55, Close $552.06, Volume 1.4M.
  • 2026-08-20: Open $543.78, High $548.99, Low $538.27, Close $540.26, Volume 1.1M.
  • 2026-08-21: Open $545.10, High $555.32, Low $540.70, Close $548.05, Volume 1.1M.
  • 2026-08-24: Open $548.98, High $550.62, Low $542.42, Close $547.59, Volume 767.4K.
  • 2026-08-25: Open $545.53, High $555.69, Low $543.75, Close $552.85, Volume 775K.
  • 2026-08-26: Open $549.84, High $553.47, Low $546.24, Close $547.29, Volume 834.1K.
  • 2026-08-27: Open $540.08, High $550.83, Low $540.08, Close $547.55, Volume 843.9K.
  • 2026-08-28: Open $547.09, High $549.57, Low $540.08, Close $541.69, Volume 886.9K.
  • 2026-08-31: Open $535.38, High $546.84, Low $532.23, Close $544.52, Volume 1.2M.
  • 2026-09-01: Open $548.60, High $551.40, Low $545.08, Close $547.65, Volume 734.9K.
  • 2026-09-02: Open $552.42, High $558.36, Low $549.07, Close $556.75, Volume 1.7M.
  • 2026-09-03: Open $559.00, High $560.25, Low $551.61, Close $557.96, Volume 800.7K.
  • 2026-09-04: Open $549.50, High $556.99, Low $544.48, Close $546.12, Volume 803.3K.
  • 2026-09-08: Open $529.64, High $535.00, Low $520.20, Close $528.90, Volume 1.1M.
  • 2026-09-09: Open $524.00, High $528.17, Low $520.08, Close $521.12, Volume 958.3K.
  • 2026-09-10: Open $519.13, High $522.60, Low $514.32, Close $514.56, Volume 815K.
  • 2026-09-11: Open $522.10, High $522.10, Low $511.81, Close $515.44, Volume 875.5K.
  • 2026-09-14: Open $522.17, High $525.29, Low $514.66, Close $519.51, Volume 836.9K.
  • 2026-09-15: Open $519.94, High $519.94, Low $511.00, Close $514.63, Volume 824.8K.
  • 2026-09-16: Open $513.80, High $517.95, Low $511.90, Close $514.86, Volume 70.5K.
  • 4 · Sale. Filed 2026-11-10. Accession 0000875320-26-000293.View filing
  • 4 · Other transactions. Filed 2026-10-22. Accession 0000875320-26-000283.View filing
  • 4 · Transaction details unavailable. Filed 2026-10-19. Accession 0000875320-26-000274.View filing

Analyst estimates

Source12M Target12M RangeAnalystsUpdated
StockAnalysis$595.36USD$350.00 – $725.00USD28—

MarketBeat data unavailable

Signal track record

First tracked2026-11-03 (9d ago)
Entry price$530.76
Initial 12M target$578.53
Initial 12M expected gap
+9.0%
Initial confidence
47%
Realized return
+2.2%+24.8% of target

Available. Fiscal quarters are based on SEC filings. Year-over-year change uses the corresponding quarter one year earlier.

Last checked

Revenue

Revenue by fiscal quarter, with SEC filing evidence
Fiscal quarterPeriodValueChange YoYSEC filing
FY2026 Q3 – 3,440,800,000 USD+11.8%
10-Q · Nov 3, 2026, accession 0000875320-26-000291 (opens in a new tab)
FY2026 Q2 – 3,333,900,000 USD+12.5%
10-Q · Aug 4, 2026, accession 0000875320-26-000259 (opens in a new tab)
FY2026 Q1 – 2,986,900,000 USD+7.8%
10-Q · May 5, 2026, accession 0000875320-26-000173 (opens in a new tab)
FY2025 Q4 – 3,190,000,000 USD+9.5%
10-K · Feb 13, 2026, accession 0000875320-26-000056 (opens in a new tab)10-Q · May 6, 2025, accession 0000875320-25-000192 (opens in a new tab)10-Q · Aug 5, 2025, accession 0000875320-25-000216 (opens in a new tab)10-Q · Nov 4, 2025, accession 0000875320-25-000232 (opens in a new tab)
FY2025 Q3 – 3,076,400,000 USD+11.0%
10-Q · Nov 4, 2025, accession 0000875320-25-000232 (opens in a new tab)
FY2025 Q2 – 2,964,700,000 USD+12.1%
10-Q · Aug 5, 2025, accession 0000875320-25-000216 (opens in a new tab)
FY2025 Q1 – 2,770,200,000 USD+3.0%
10-Q · May 6, 2025, accession 0000875320-25-000192 (opens in a new tab)
FY2024 Q4 – 2,912,000,000 USD+15.7%
10-K · Feb 13, 2025, accession 0000875320-25-000053 (opens in a new tab)10-Q · May 7, 2024, accession 0000875320-24-000139 (opens in a new tab)10-Q · Aug 2, 2024, accession 0000875320-24-000198 (opens in a new tab)10-Q · Nov 5, 2024, accession 0000875320-24-000223 (opens in a new tab)

Net income or loss

Net income or loss by fiscal quarter, with SEC filing evidence
Fiscal quarterPeriodValueChange YoYSEC filing
FY2026 Q3 – 653,600,000 USD-39.6%
10-Q · Nov 3, 2026, accession 0000875320-26-000291 (opens in a new tab)
FY2026 Q2 – 1,099,800,000 USD+6.5%
10-Q · Aug 4, 2026, accession 0000875320-26-000259 (opens in a new tab)
FY2026 Q1 – 1,031,400,000 USD+59.6%
10-Q · May 5, 2026, accession 0000875320-26-000173 (opens in a new tab)
FY2025 Q4 – 1,191,100,000 USD+30.5%
10-K · Feb 13, 2026, accession 0000875320-26-000056 (opens in a new tab)10-Q · May 6, 2025, accession 0000875320-25-000192 (opens in a new tab)10-Q · Aug 5, 2025, accession 0000875320-25-000216 (opens in a new tab)10-Q · Nov 4, 2025, accession 0000875320-25-000232 (opens in a new tab)
FY2025 Q3 – 1,082,900,000 USD+3.6%
10-Q · Nov 4, 2025, accession 0000875320-25-000232 (opens in a new tab)
FY2025 Q2 – 1,032,900,000 USD+128.7%
10-Q · Aug 5, 2025, accession 0000875320-25-000216 (opens in a new tab)
FY2025 Q1 – 646,300,000 USD-41.2%
10-Q · May 6, 2025, accession 0000875320-25-000192 (opens in a new tab)
FY2024 Q4 – 913,000,000 USD-5.8%
10-K · Feb 13, 2025, accession 0000875320-25-000053 (opens in a new tab)10-Q · May 7, 2024, accession 0000875320-24-000139 (opens in a new tab)10-Q · Aug 2, 2024, accession 0000875320-24-000198 (opens in a new tab)10-Q · Nov 5, 2024, accession 0000875320-24-000223 (opens in a new tab)

Operating cash flow

Operating cash flow by fiscal quarter, with SEC filing evidence
Fiscal quarterPeriodValueChange YoYSEC filing
FY2026 Q3 – 643,100,000 USD-48.2%
10-Q · Nov 3, 2026, accession 0000875320-26-000291 (opens in a new tab)10-Q · Aug 4, 2026, accession 0000875320-26-000259 (opens in a new tab)
FY2026 Q2 – 1,125,400,000 USD+4.9%
10-Q · Aug 4, 2026, accession 0000875320-26-000259 (opens in a new tab)10-Q · May 5, 2026, accession 0000875320-26-000173 (opens in a new tab)
FY2026 Q1 – 1,428,100,000 USD+74.4%
10-Q · May 5, 2026, accession 0000875320-26-000173 (opens in a new tab)
FY2025 Q4 – 498,000,000 USD-14.8%
10-K · Feb 13, 2026, accession 0000875320-26-000056 (opens in a new tab)10-Q · May 6, 2025, accession 0000875320-25-000192 (opens in a new tab)10-Q · Aug 5, 2025, accession 0000875320-25-000216 (opens in a new tab)10-Q · Nov 4, 2025, accession 0000875320-25-000232 (opens in a new tab)
FY2025 Q3 – 1,241,400,000 USD-9.4%
10-Q · Nov 4, 2025, accession 0000875320-25-000232 (opens in a new tab)10-Q · Aug 5, 2025, accession 0000875320-25-000216 (opens in a new tab)
FY2025 Q2 – 1,073,100,000 USD+128.6%
10-Q · Aug 5, 2025, accession 0000875320-25-000216 (opens in a new tab)10-Q · May 6, 2025, accession 0000875320-25-000192 (opens in a new tab)
FY2025 Q1 – 818,900,000 USD-37.3%
10-Q · May 6, 2025, accession 0000875320-25-000192 (opens in a new tab)
FY2024 Q4 – 584,600,000 USD+149.2%
10-K · Feb 13, 2025, accession 0000875320-25-000053 (opens in a new tab)10-Q · May 7, 2024, accession 0000875320-24-000139 (opens in a new tab)10-Q · Aug 2, 2024, accession 0000875320-24-000198 (opens in a new tab)10-Q · Nov 5, 2024, accession 0000875320-24-000223 (opens in a new tab)

Insider activity

1 sale, 4 other transactions reported.

Available · Checked Nov 13, 2026

View reported transactions (5 rows · 7 filings)

SaleKewalramani Reshma

View Form 4 filing at SEC

Filing context

Reporting owners and roles: Kewalramani Reshma (director, officer (CEO & President))

10b5-1 declared for this filing

  • Kewalramani ReshmaSale11,866 shares · $6,307,134.98
    Transaction details

    director, officer (CEO & President) · Direct ownership · Common Stock · Code S/D · 12.07% of before-trade holdings

Other transactionsBrennan Daniel J.

View Form 4 filing at SEC

Filing context

Reporting owners and roles: Brennan Daniel J. (director)

  • Brennan Daniel J.Grant, award or other acquisition795 shares · $400,258.65
    Transaction details

    director · Direct ownership · Common Stock · Code A/A

Transaction details unavailableGarber Alan M

View Form 4 filing at SEC

Filing context

Reporting owners and roles: Garber Alan M (director)

Transaction details unavailable.

Transaction details unavailableSACHS BRUCE I

View Form 4 filing at SEC

Filing context

Reporting owners and roles: SACHS BRUCE I (director)

Transaction details unavailable.

Other transactionsvan Grunsven Jasper

View Form 4 filing at SEC

Filing context

Reporting owners and roles: van Grunsven Jasper (officer (EVP, CP and NPPO))

  • van Grunsven JasperGrant, award or other acquisition8,682 shares · Value unavailable
    Transaction details

    officer (EVP, CP and NPPO) · Direct ownership · Common Stock · Code A/A

Other transactionsAmbrose Kristen

View Form 4 filing at SEC

Filing context

Reporting owners and roles: Ambrose Kristen (officer (SVP & Chief Accounting Officer))

  • Ambrose KristenGrant, award or other acquisition5,000 shares · Value unavailable
    Transaction details

    officer (SVP & Chief Accounting Officer) · Direct ownership · Common Stock · Code A/A

Other transactionsSACHS BRUCE I

View Form 4 filing at SEC

Filing context

Reporting owners and roles: SACHS BRUCE I (director)

  • SACHS BRUCE IGift6,000 shares · Value unavailable
    Transaction details

    director · Direct ownership · Common Stock · Code G/D

Options, grants, withholding, and gifts are context, not voluntary market purchases or sales.

Reported sales can reflect planned or tax-related transactions and do not by themselves indicate a view on the stock.

Purchase and sale labels describe reported transaction codes; they do not indicate whether the transaction is favorable.